Cell atlas - IL36B - The Human Protein Atlas

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IL36B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	IL36B
Gene description	Interleukin 36, beta
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (U-87 MG)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (U-87 MG) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	IL36B (HGNC Symbol)
Synonyms	FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882
Description	Interleukin 36, beta (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q14.1
Chromosome location (bp)	113022091 - 113052867
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000136696 (version 83.38)
Entrez gene	27177
UniProt	Q9NZH7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NZH7
Antibodypedia	IL36B antibodies

PROTEIN BROWSER

IL36B-001	IL36B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IL36B-001 ENSP00000259213 ENST00000259213	Q9NZH7 [Direct mapping] Interleukin-36 beta Show all	Predicted intracellular proteins Show all	GO:0001819 [positive regulation of cytokine production] GO:0002437 [inflammatory response to antigenic stimulus] GO:0005125 [cytokine activity] GO:0005149 [interleukin-1 receptor binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006955 [immune response] GO:0019221 [cytokine-mediated signaling pathway] GO:0032755 [positive regulation of interleukin-6 production] GO:0045087 [innate immune response] GO:0045582 [positive regulation of T cell differentiation] Show all	164 aa 18.5 kDa	No	0
IL36B-002 ENSP00000328420 ENST00000327407	Q9NZH7 [Direct mapping] Interleukin-36 beta Show all	Predicted intracellular proteins Show all	GO:0002437 [inflammatory response to antigenic stimulus] GO:0005125 [cytokine activity] GO:0005149 [interleukin-1 receptor binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006955 [immune response] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] Show all	157 aa 17.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.