Expression of UGGT1 in cancer - Summary

CANCER ATLAS

Gene description

UDP-glucose glycoprotein glucosyltransferase 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA012761	HPA015127

GENE INFORMATION
Gene name	UGGT1 (HGNC Symbol)
Synonyms	HUGT1, UGCGL1
Description	UDP-glucose glycoprotein glucosyltransferase 1 (HGNC Symbol)
Entrez gene summary	UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Chromosome	2
Cytoband	q14.3
Chromosome location (bp)	128091200 - 128195677
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136731 (version 83.38)
Entrez gene	56886
UniProt	Q9NYU2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NYU2
Antibodypedia	UGGT1 antibodies

PROTEIN BROWSER

UGGT1-001	UGGT1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UGGT1-001 ENSP00000259253 ENST00000259253	Q9NYU2 [Direct mapping] UDP-glucose:glycoprotein glucosyltransferase 1 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003980 [UDP-glucose:glycoprotein glucosyltransferase activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006457 [protein folding] GO:0006486 [protein glycosylation] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0051082 [unfolded protein binding] GO:0051084 ['de novo' posttranslational protein folding] GO:0070062 [extracellular exosome] GO:0097359 [UDP-glucosylation] Show all	1555 aa 177.2 kDa	No	0
UGGT1-007 ENSP00000389441 ENST00000418197	H7BZG0 [Direct mapping] UDP-glucose:glycoprotein glucosyltransferase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003980 [UDP-glucose:glycoprotein glucosyltransferase activity] GO:0006486 [protein glycosylation] GO:0097359 [UDP-glucosylation] Show all	131 aa 15.5 kDa	No	0