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UGGT1

GENERAL INFORMATION

Gene name

 UGGT1

Gene description

 UDP-glucose glycoprotein glucosyltransferase 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression with a granular pattern in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA012761 , HPA015127
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 UGGT1 (HGNC Symbol)

Synonyms

 HUGT1, UGCGL1

Description

 UDP-glucose glycoprotein glucosyltransferase 1 (HGNC Symbol)

Entrez gene summary

 UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

Chromosome

 2

Cytoband

 q14.3

Chromosome location (bp)

 128091200 - 128195677

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136731 (version 83.38)

Entrez gene

 56886

UniProt

 Q9NYU2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NYU2

Antibodypedia

 UGGT1 antibodies

PROTEIN BROWSER
UGGT1-001
UGGT1-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UGGT1-001
ENSP00000259253
ENST00000259253
Q9NYU2 [Direct mapping]
UDP-glucose:glycoprotein glucosyltransferase 1
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   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003980 [UDP-glucose:glycoprotein glucosyltransferase activity]
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0006457 [protein folding]
GO:0006486 [protein glycosylation]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0051082 [unfolded protein binding]
GO:0051084 ['de novo' posttranslational protein folding]
GO:0070062 [extracellular exosome]
GO:0097359 [UDP-glucosylation]
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 1555 aa
177.2 kDa 		No 0
UGGT1-007
ENSP00000389441
ENST00000418197
H7BZG0 [Direct mapping]
UDP-glucose:glycoprotein glucosyltransferase 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003980 [UDP-glucose:glycoprotein glucosyltransferase activity]
GO:0006486 [protein glycosylation]
GO:0097359 [UDP-glucosylation]
Show all
 131 aa
15.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.