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UNC45A

CANCER ATLAS

Gene description

 Unc-45 myosin chaperone A

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA039228

GENE INFORMATION

Gene name

 UNC45A (HGNC Symbol)

Synonyms

 GC-UNC45, SMAP-1

Description

 Unc-45 myosin chaperone A (HGNC Symbol)

Entrez gene summary

 UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008]

Chromosome

 15

Cytoband

 q26.1

Chromosome location (bp)

 90930180 - 90954093

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140553 (version 83.38)

Entrez gene

 55898

UniProt

 Q9H3U1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H3U1

Antibodypedia

 UNC45A antibodies

PROTEIN BROWSER
UNC45A-001
UNC45A-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UNC45A-001
ENSP00000377816
ENST00000394275
Q9H3U1 [Direct mapping]
Protein unc-45 homolog A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0007517 [muscle organ development]
GO:0030154 [cell differentiation]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 929 aa
101.7 kDa 		No 0
UNC45A-002
ENSP00000407487
ENST00000418476
Q9H3U1 [Direct mapping]
Protein unc-45 homolog A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0007517 [muscle organ development]
GO:0030154 [cell differentiation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051879 [Hsp90 protein binding]
GO:0061077 [chaperone-mediated protein folding]
Show all
 944 aa
103.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.