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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RPRD1A
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RPRD1A

Gene description

Regulation of nuclear pre-mRNA domain containing 1A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General nuclear expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
HPA040602
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RPRD1A (HGNC Symbol)

Synonyms

FLJ10656, HsT3101, P15RS

Description

Regulation of nuclear pre-mRNA domain containing 1A (HGNC Symbol)

Entrez gene summary

This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16. [provided by RefSeq, Dec 2014]

Chromosome

18

Cytoband

q12.2

Chromosome location (bp)

35984387 - 36067576

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141425 (version 83.38)

Entrez gene

55197

UniProt

Q96P16 (UniProt - Evidence at protein level)

neXtProt

NX_Q96P16

Antibodypedia

RPRD1A antibodies

PROTEIN BROWSER

RPRD1A-001
RPRD1A-002
RPRD1A-004
RPRD1A-005
RPRD1A-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPRD1A-001
ENSP00000381984
ENST00000399022
Q96P16 [Direct mapping]
Regulation of nuclear pre-mRNA domain-containing protein 1A
A0A024RC37 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0016591 [DNA-directed RNA polymerase II, holoenzyme]
GO:0070940 [dephosphorylation of RNA polymerase II C-terminal domain]
Show all
312 aa
35.7 kDa
No 0
RPRD1A-002
ENSP00000465444
ENST00000588737
Q96P16 [Direct mapping]
Regulation of nuclear pre-mRNA domain-containing protein 1A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0016591 [DNA-directed RNA polymerase II, holoenzyme]
GO:0070940 [dephosphorylation of RNA polymerase II C-terminal domain]
Show all
276 aa
31.6 kDa
No 0
RPRD1A-004
ENSP00000349955
ENST00000357384
Q96P16 [Direct mapping]
Regulation of nuclear pre-mRNA domain-containing protein 1A
A0A024RC37 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0016591 [DNA-directed RNA polymerase II, holoenzyme]
GO:0070940 [dephosphorylation of RNA polymerase II C-terminal domain]
Show all
312 aa
35.7 kDa
No 0
RPRD1A-005
ENSP00000467991
ENST00000590898
Q96P16 [Direct mapping]
Regulation of nuclear pre-mRNA domain-containing protein 1A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0016591 [DNA-directed RNA polymerase II, holoenzyme]
GO:0070940 [dephosphorylation of RNA polymerase II C-terminal domain]
Show all
276 aa
31.6 kDa
No 0
RPRD1A-009
ENSP00000467268
ENST00000585953
K7EP82 [Direct mapping]
Regulation of nuclear pre-mRNA domain-containing protein 1A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
123 aa
13.6 kDa
No 0

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