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LMO4

GENERAL INFORMATION

Gene name

 LMO4

Gene description

 LIM domain only 4

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA061638 , CAB022345
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 LMO4

Synonyms

Description

 LIM domain only 4 (HGNC Symbol)

Entrez gene summary

 This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]

Chromosome

 1

Cytoband

 p22.3

Chromosome location (bp)

 87328468 - 87348923

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000143013 (version 83.38)

Entrez gene

 8543

UniProt

 P61968 (UniProt - Evidence at protein level)

neXtProt

 NX_P61968

Antibodypedia

 LMO4 antibodies

PROTEIN BROWSER
LMO4-001
LMO4-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LMO4-001
ENSP00000359575
ENST00000370544
P61968 [Direct mapping]
LIM domain transcription factor LMO4
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001158 [enhancer sequence-specific DNA binding]
GO:0001843 [neural tube closure]
GO:0003281 [ventricular septum development]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005667 [transcription factor complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0008134 [transcription factor binding]
GO:0008270 [zinc ion binding]
GO:0021514 [ventral spinal cord interneuron differentiation]
GO:0021522 [spinal cord motor neuron differentiation]
GO:0021527 [spinal cord association neuron differentiation]
GO:0031333 [negative regulation of protein complex assembly]
GO:0042659 [regulation of cell fate specification]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048538 [thymus development]
GO:0050865 [regulation of cell activation]
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 165 aa
18 kDa 		No 0
LMO4-002
ENSP00000359573
ENST00000370542
P61968 [Direct mapping]
LIM domain transcription factor LMO4
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001843 [neural tube closure]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005667 [transcription factor complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0008134 [transcription factor binding]
GO:0008270 [zinc ion binding]
Show all
 165 aa
18 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.