Tissue expression of ADAMTS19 - Summary - The Human Protein Atlas

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ADAMTS19

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ADAMTS19
Gene description	ADAM metallopeptidase with thrombospondin type 1 motif, 19
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (cervix, uterine, endometrium, smooth muscle, placenta)
GTEx:	Tissue enhanced (endometrium, cervix, uterine)
FANTOM5:	Group enriched (endometrium, cervix, uterine)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA056171
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cervix, uterine, endometrium, smooth muscle, placenta)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (endometrium, cervix, uterine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (endometrium, cervix, uterine)

GENE INFORMATION
Gene name	ADAMTS19
Synonyms
Description	ADAM metallopeptidase with thrombospondin type 1 motif, 19 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q23.3
Chromosome location (bp)	129460265 - 129738683
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000145808 (version 83.38)
Entrez gene	171019
UniProt	Q8TE59 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TE59
Antibodypedia	ADAMTS19 antibodies

PROTEIN BROWSER

ADAMTS19-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADAMTS19-001 ENSP00000274487 ENST00000274487	Q8TE59 [Direct mapping] A disintegrin and metalloproteinase with thrombospondin motifs 19 Show all	Enzymes Peptidases Metallopeptidases SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Show all	GO:0004222 [metalloendopeptidase activity] GO:0005578 [proteinaceous extracellular matrix] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] GO:0008270 [zinc ion binding] GO:0031012 [extracellular matrix] Show all	1207 aa 134 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.