Cell atlas - SLC18B1 - The Human Protein Atlas

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SLC18B1

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Golgi apparatus

Human cell
	Cytosol
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	SLC18B1
Gene description	Solute carrier family 18, subfamily B, member 1
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the Golgi apparatus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)
Additional location	In addition localized to the Golgi apparatus (approved)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA029747 , HPA049659
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the Golgi apparatus.

Main location

Cytosol (supported)

Additional location

Golgi apparatus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA029747	A-431	Golgi apparatus
	HPA029747	A-431	Cytosol
	HPA029747	U-2 OS	Golgi apparatus
	HPA029747	U-2 OS	Cytosol
	HPA029747	U-251 MG	Golgi apparatus
	HPA029747	U-251 MG	Cytosol
	HPA049659	A-431	Cytosol
	HPA049659	U-2 OS	Cytosol
	HPA049659	U-251 MG	Cytosol

GENE INFORMATION
Gene name	SLC18B1 (HGNC Symbol)
Synonyms	C6orf192, dJ55C23.6
Description	Solute carrier family 18, subfamily B, member 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	q23.2
Chromosome location (bp)	132769370 - 132798553
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146409 (version 83.38)
Entrez gene	116843
UniProt	Q6NT16 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NT16
Antibodypedia	SLC18B1 antibodies

PROTEIN BROWSER

SLC18B1-001	SLC18B1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC18B1-001 ENSP00000275227 ENST00000275227	Q6NT16 [Direct mapping] MFS-type transporter SLC18B1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	456 aa 48.9 kDa	No	>9
SLC18B1-002 ENSP00000356895 ENST00000367918	Q5TBJ2 [Direct mapping] MFS-type transporter SLC18B1 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	107 aa 11.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.