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MEPCE

GENERAL INFORMATION

Gene name

 MEPCE

Gene description

 Methylphosphate capping enzyme

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 2 antibodies.
HPA051587 , CAB026384
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MEPCE (HGNC Symbol)

Synonyms

 BCDIN3, FLJ20257, MePCE

Description

 Methylphosphate capping enzyme (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 q22.1

Chromosome location (bp)

 100428790 - 100434126

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000146834 (version 83.38)

Entrez gene

 56257

UniProt

 Q7L2J0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7L2J0

Antibodypedia

 MEPCE antibodies

PROTEIN BROWSER
MEPCE-001
MEPCE-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MEPCE-001
ENSP00000308546
ENST00000310512
Q7L2J0 [Direct mapping]
7SK snRNA methylphosphate capping enzyme
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001510 [RNA methylation]
GO:0008168 [methyltransferase activity]
GO:0008173 [RNA methyltransferase activity]
GO:0008757 [S-adenosylmethionine-dependent methyltransferase activity]
GO:0016073 [snRNA metabolic process]
GO:0035562 [negative regulation of chromatin binding]
GO:0040031 [snRNA modification]
GO:0044822 [poly(A) RNA binding]
GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle]
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 689 aa
74.4 kDa 		No 0
MEPCE-002
ENSP00000400875
ENST00000414441
Q7L2J0 [Direct mapping]
7SK snRNA methylphosphate capping enzyme
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001510 [RNA methylation]
GO:0008168 [methyltransferase activity]
GO:0008173 [RNA methyltransferase activity]
GO:0008757 [S-adenosylmethionine-dependent methyltransferase activity]
GO:0016073 [snRNA metabolic process]
GO:0040031 [snRNA modification]
GO:0044822 [poly(A) RNA binding]
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 220 aa
24.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.