Expression of GPR174 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 174

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041025

GENE INFORMATION
Gene name	GPR174 (HGNC Symbol)
Synonyms	FKSG79
Description	G protein-coupled receptor 174 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	79170972 - 79172229
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147138 (version 83.38)
Entrez gene	84636
UniProt	Q9BXC1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BXC1
Antibodypedia	GPR174 antibodies

PROTEIN BROWSER

GPR174-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR174-001 ENSP00000276077 ENST00000276077	Q9BXC1 [Direct mapping] Probable G-protein coupled receptor 174 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0043029 [T cell homeostasis] GO:0045125 [bioactive lipid receptor activity] Show all	333 aa 38.5 kDa	No	7