Fields »
ABOUT
HELP
BLOG
GPR174

GENERAL INFORMATION

Gene name

 GPR174

Gene description

 G protein-coupled receptor 174

Protein class

 G-protein coupled receptors
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (lymph node, tonsil, spleen)
GTEx:Tissue enhanced (spleen, small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in subsets of immune cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.

Reliability score

 Supported based on 1 antibody.
HPA041025
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Spleen

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node, tonsil, spleen)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen, small intestine)

GENE INFORMATION

Gene name

 GPR174 (HGNC Symbol)

Synonyms

 FKSG79

Description

 G protein-coupled receptor 174 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]

Chromosome

 X

Cytoband

 q21.1

Chromosome location (bp)

 79170972 - 79172229

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147138 (version 83.38)

Entrez gene

 84636

UniProt

 Q9BXC1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9BXC1

Antibodypedia

 GPR174 antibodies

PROTEIN BROWSER
GPR174-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GPR174-001
ENSP00000276077
ENST00000276077
Q9BXC1 [Direct mapping]
Probable G-protein coupled receptor 174
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
   Adenosine and adenine nucleotide receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0043029 [T cell homeostasis]
GO:0045125 [bioactive lipid receptor activity]
Show all
 333 aa
38.5 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.