Cell atlas - GPR174 - The Human Protein Atlas

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GPR174

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	GPR174
Gene description	G protein-coupled receptor 174
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Cell line enriched (MOLT-4)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA041025
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (MOLT-4) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041025	A-431	Vesicles
	HPA041025	U-2 OS	No staining
	HPA041025	U-251 MG	No staining

GENE INFORMATION
Gene name	GPR174 (HGNC Symbol)
Synonyms	FKSG79
Description	G protein-coupled receptor 174 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	79170972 - 79172229
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147138 (version 83.38)
Entrez gene	84636
UniProt	Q9BXC1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BXC1
Antibodypedia	GPR174 antibodies

PROTEIN BROWSER

GPR174-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR174-001 ENSP00000276077 ENST00000276077	Q9BXC1 [Direct mapping] Probable G-protein coupled receptor 174 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0043029 [T cell homeostasis] GO:0045125 [bioactive lipid receptor activity] Show all	333 aa 38.5 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.