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CAMK2G

CANCER ATLAS

Gene description

 Calcium/calmodulin-dependent protein kinase II gamma

Protein class

 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Glioma

STAINING SUMMARY
HPA051783
HPA051785
HPA053973

GENE INFORMATION

Gene name

 CAMK2G (HGNC Symbol)

Synonyms

 CAMKG

Description

 Calcium/calmodulin-dependent protein kinase II gamma (HGNC Symbol)

Entrez gene summary

 The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

Chromosome

 10

Cytoband

 q22.2

Chromosome location (bp)

 73812501 - 73874591

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000148660 (version 83.38)

Entrez gene

 818

UniProt

 Q13555 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13555

Antibodypedia

 CAMK2G antibodies

PROTEIN BROWSER
CAMK2G-001
CAMK2G-002
CAMK2G-003
CAMK2G-004
CAMK2G-005
CAMK2G-010
CAMK2G-201
CAMK2G-202
CAMK2G-203

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CAMK2G-001
ENSP00000315599
ENST00000322635
Q13555 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0004723 [calcium-dependent protein serine/threonine phosphatase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006470 [protein dephosphorylation]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0016020 [membrane]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030073 [insulin secretion]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051259 [protein oligomerization]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1900034 [regulation of cellular response to heat]
Show all
 527 aa
59 kDa 		No 1
CAMK2G-002
ENSP00000277853
ENST00000351293
Q13555 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0004723 [calcium-dependent protein serine/threonine phosphatase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006470 [protein dephosphorylation]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0016020 [membrane]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030073 [insulin secretion]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051259 [protein oligomerization]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1900034 [regulation of cellular response to heat]
Show all
 495 aa
56 kDa 		No 1
CAMK2G-003
ENSP00000393784
ENST00000433289
Q8WU40 [Direct mapping]
CAMK2G protein; Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 453 aa
50.9 kDa 		No 1
CAMK2G-004
ENSP00000361851
ENST00000372765
Q5SWX3 [Direct mapping]
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, isoform CRA_n; Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 516 aa
57.8 kDa 		No 1
CAMK2G-005
ENSP00000307082
ENST00000305762
Q13555 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0004723 [calcium-dependent protein serine/threonine phosphatase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006470 [protein dephosphorylation]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0016020 [membrane]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030073 [insulin secretion]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051259 [protein oligomerization]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1900034 [regulation of cellular response to heat]
Show all
 529 aa
59.6 kDa 		No 1
CAMK2G-010
ENSP00000405561
ENST00000441192
H0Y6G2 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 335 aa
36.9 kDa 		No 0
CAMK2G-201
ENSP00000319060
ENST00000322680
Q13555 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0004723 [calcium-dependent protein serine/threonine phosphatase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006470 [protein dephosphorylation]
GO:0006816 [calcium ion transport]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0016020 [membrane]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030073 [insulin secretion]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051259 [protein oligomerization]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0097481 [neuronal postsynaptic density]
GO:1900034 [regulation of cellular response to heat]
GO:1901897 [regulation of relaxation of cardiac muscle]
Show all
 556 aa
62.2 kDa 		No 1
CAMK2G-202
ENSP00000378243
ENST00000394762
A0A0A0MS52 [Direct mapping]
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, isoform CRA_a; Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 539 aa
60.2 kDa 		No 1
CAMK2G-203
ENSP00000410298
ENST00000423381
A0A0A0MT11 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 558 aa
62.6 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.