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KLHL1

CANCER ATLAS

Gene description

 Kelch-like family member 1

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at transcript level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA021196

GENE INFORMATION

Gene name

 KLHL1 (HGNC Symbol)

Synonyms

 FLJ30047, KIAA1490, MRP2

Description

 Kelch-like family member 1 (HGNC Symbol)

Entrez gene summary

 The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010]

Chromosome

 13

Cytoband

 q21.33

Chromosome location (bp)

 69700594 - 70108493

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000150361 (version 83.38)

Entrez gene

 57626

UniProt

 Q9NR64 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9NR64

Antibodypedia

 KLHL1 antibodies

PROTEIN BROWSER
KLHL1-001
KLHL1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KLHL1-001
ENSP00000367075
ENST00000377844
Q9NR64 [Direct mapping]
Kelch-like protein 1
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Predicted intracellular proteins
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GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0007626 [locomotory behavior]
GO:0007628 [adult walking behavior]
GO:0016358 [dendrite development]
GO:0016567 [protein ubiquitination]
GO:0021680 [cerebellar Purkinje cell layer development]
GO:0030036 [actin cytoskeleton organization]
GO:0030425 [dendrite]
GO:0031463 [Cul3-RING ubiquitin ligase complex]
GO:0043025 [neuronal cell body]
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 748 aa
82.7 kDa 		No 0
KLHL1-201
ENSP00000439602
ENST00000545028
F5H1J3 [Direct mapping]
Kelch-like protein 1
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Predicted intracellular proteins
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GO:0005515 [protein binding]
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 687 aa
75.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.