Cell atlas - KLHL1 - The Human Protein Atlas

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KLHL1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	KLHL1
Gene description	Kelch-like family member 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (HeLa)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (HeLa) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	KLHL1 (HGNC Symbol)
Synonyms	FLJ30047, KIAA1490, MRP2
Description	Kelch-like family member 1 (HGNC Symbol)
Entrez gene summary	The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010]
Chromosome	13
Cytoband	q21.33
Chromosome location (bp)	69700594 - 70108493
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000150361 (version 83.38)
Entrez gene	57626
UniProt	Q9NR64 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NR64
Antibodypedia	KLHL1 antibodies

PROTEIN BROWSER

KLHL1-001	KLHL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KLHL1-001 ENSP00000367075 ENST00000377844	Q9NR64 [Direct mapping] Kelch-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0003779 [actin binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0007626 [locomotory behavior] GO:0007628 [adult walking behavior] GO:0016358 [dendrite development] GO:0016567 [protein ubiquitination] GO:0021680 [cerebellar Purkinje cell layer development] GO:0030036 [actin cytoskeleton organization] GO:0030425 [dendrite] GO:0031463 [Cul3-RING ubiquitin ligase complex] GO:0043025 [neuronal cell body] Show all	748 aa 82.7 kDa	No	0
KLHL1-201 ENSP00000439602 ENST00000545028	F5H1J3 [Direct mapping] Kelch-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	687 aa 75.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.