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RAB3C

GENERAL INFORMATION

Gene name

 RAB3C

Gene description

 RAB3C, member RAS oncogene family

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (cerebral cortex, adrenal gland)
GTEx:Group enriched (hypothalamus, cerebral cortex, caudate, hippocampus, pituitary gland, cerebellum)
FANTOM5:Group enriched (hippocampus, pituitary gland, caudate, brain, cerebellum)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in CNS, adrenal medulla and islets of Langerhans.

DATA RELIABILITY

Data reliability
description

 Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA003160
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebral cortex, adrenal gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (hypothalamus, cerebral cortex, caudate, hippocampus, pituitary gland, cerebellum)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (hippocampus, pituitary gland, caudate, brain, cerebellum)

GENE INFORMATION

Gene name

 RAB3C

Synonyms

Description

 RAB3C, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

 RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments (Cheng et al., 2002 [PubMed 12296628]).[supplied by OMIM, Jun 2009]

Chromosome

 5

Cytoband

 q11.2

Chromosome location (bp)

 58582221 - 58859394

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000152932 (version 83.38)

Entrez gene

 115827

UniProt

 Q96E17 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96E17

Antibodypedia

 RAB3C antibodies

PROTEIN BROWSER
RAB3C-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB3C-001
ENSP00000282878
ENST00000282878
Q96E17 [Direct mapping]
Ras-related protein Rab-3C
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008021 [synaptic vesicle]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017157 [regulation of exocytosis]
GO:0019882 [antigen processing and presentation]
GO:0030667 [secretory granule membrane]
GO:0031489 [myosin V binding]
GO:0031982 [vesicle]
GO:0032482 [Rab protein signal transduction]
GO:0048471 [perinuclear region of cytoplasm]
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 227 aa
26 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.