We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Many cholangiocarcinomas, colorectal, ovarian, cervical, gastric and pancreatic cancers moderate to strong cytoplasmic and membranous positivity. Remaining cancer cells were in general weakly stained or negative.
GENE INFORMATION
Gene name
TYSND1 (HGNC Symbol)
Synonyms
MGC34695, NET41
Description
Trypsin domain containing 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
