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RRP1

GENERAL INFORMATION

Gene name

 RRP1

Gene description

 Ribosomal RNA processing 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nucleolar expression in several cell types with highest levels in neuronal cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 2 antibodies.
HPA016818 , HPA018166
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RRP1 (HGNC Symbol)

Synonyms

 D21S2056E, NNP-1, Nop52, RRP1A

Description

 Ribosomal RNA processing 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]

Chromosome

 21

Cytoband

 q22.3

Chromosome location (bp)

 43789513 - 43805293

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000160214 (version 83.38)

Entrez gene

 8568

UniProt

 P56182 (UniProt - Evidence at protein level)

neXtProt

 NX_P56182

Antibodypedia

 RRP1 antibodies

PROTEIN BROWSER
RRP1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RRP1-001
ENSP00000417464
ENST00000497547
P56182 [Direct mapping]
Ribosomal RNA processing protein 1 homolog A
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006364 [rRNA processing]
GO:0030688 [preribosome, small subunit precursor]
GO:0044822 [poly(A) RNA binding]
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 461 aa
52.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.