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B3GALNT2

GENERAL INFORMATION

Gene name

 B3GALNT2

Gene description

 Beta-1,3-N-acetylgalactosaminyltransferase 2

Protein class

 Disease related genes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several different tissue types.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA050662
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 B3GALNT2 (HGNC Symbol)

Synonyms

 MGC39558

Description

 Beta-1,3-N-acetylgalactosaminyltransferase 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the glycosyltransferase 31 family. The encoded protein synthesizes GalNAc:beta-1,3GlcNAc, a novel carbohydrate structure, on N- and O-glycans. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2013]

Chromosome

 1

Cytoband

 q42.3

Chromosome location (bp)

 235449923 - 235504481

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162885 (version 83.38)

Entrez gene

 148789

UniProt

 Q8NCR0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NCR0

Antibodypedia

 B3GALNT2 antibodies

PROTEIN BROWSER
B3GALNT2-001
B3GALNT2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
B3GALNT2-001
ENSP00000355559
ENST00000366600
Q8NCR0 [Direct mapping]
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005783 [endoplasmic reticulum]
GO:0006486 [protein glycosylation]
GO:0006493 [protein O-linked glycosylation]
GO:0008375 [acetylglucosaminyltransferase activity]
GO:0008376 [acetylgalactosaminyltransferase activity]
GO:0008378 [galactosyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 500 aa
56.7 kDa 		Yes 0
B3GALNT2-002
ENSP00000315678
ENST00000313984
Q8NCR0 [Direct mapping]
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
Show all
   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005783 [endoplasmic reticulum]
GO:0006486 [protein glycosylation]
GO:0006493 [protein O-linked glycosylation]
GO:0008375 [acetylglucosaminyltransferase activity]
GO:0008376 [acetylgalactosaminyltransferase activity]
GO:0008378 [galactosyltransferase activity]
GO:0016021 [integral component of membrane]
Show all
 326 aa
35.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.