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SUN1
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

SUN1

Gene description

Sad1 and UNC84 domain containing 1

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

17
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General nuclear membranous expression.

DATA RELIABILITY

Data reliability
description

Antibody staining consistent with RNA expression data.

Reliability score

Supported based on 2 antibodies.
HPA008346 , HPA008461
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin020406080100120TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin010203040506070RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina020406080100120140Tags Per Million

GENE INFORMATION

Gene name

SUN1 (HGNC Symbol)

Synonyms

FLJ12407, KIAA0810, UNC84A

Description

Sad1 and UNC84 domain containing 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2010]

Chromosome

7

Cytoband

p22.3

Chromosome location (bp)

816615 - 896435

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164828 (version 83.38)

Entrez gene

23353

UniProt

O94901 (UniProt - Evidence at protein level)

neXtProt

NX_O94901

Antibodypedia

SUN1 antibodies

PROTEIN BROWSER

«
SUN1-001
SUN1-002
SUN1-005
SUN1-007
SUN1-008
SUN1-012
SUN1-013
SUN1-015
SUN1-016
SUN1-017
SUN1-018
SUN1-019
SUN1-024
SUN1-027
SUN1-201
SUN1-202
SUN1-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SUN1-001
ENSP00000384116
ENST00000405266
E9PHI4 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
GO:0031965 [nuclear membrane]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
822 aa
91.1 kDa
No 3
SUN1-002
ENSP00000374225
ENST00000389574
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0006998 [nuclear envelope organization]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
702 aa
77.9 kDa
No 2
SUN1-005
ENSP00000384015
ENST00000401592
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001503 [ossification]
GO:0002080 [acrosomal membrane]
GO:0005515 [protein binding]
GO:0005521 [lamin binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005639 [integral component of nuclear inner membrane]
GO:0005737 [cytoplasm]
GO:0006998 [nuclear envelope organization]
GO:0007129 [synapsis]
GO:0009612 [response to mechanical stimulus]
GO:0016021 [integral component of membrane]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
785 aa
87.1 kDa
No 2
SUN1-007
ENSP00000383947
ENST00000403868
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0006998 [nuclear envelope organization]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
257 aa
28.1 kDa
No 0
SUN1-008
ENSP00000409909
ENST00000429178
H0Y742 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
GO:0031965 [nuclear membrane]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
710 aa
79.6 kDa
No 2
SUN1-012
ENSP00000406653
ENST00000433212
H0Y6N5 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
634 aa
70.9 kDa
No 3
SUN1-013
ENSP00000388430
ENST00000435699
C9JK55 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
174 aa
18.8 kDa
No 0
SUN1-015
ENSP00000399549
ENST00000440380
C9JR15 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
88 aa
9.5 kDa
No 0
SUN1-016
ENSP00000413188
ENST00000439679
C9K051 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
135 aa
14.6 kDa
No 0
SUN1-017
ENSP00000394597
ENST00000424128
C9JR15 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
88 aa
9.5 kDa
No 0
SUN1-018
ENSP00000404965
ENST00000457598
C9JJU6 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
119 aa
12.9 kDa
No 0
SUN1-019
ENSP00000394381
ENST00000421580
C9JS54 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
113 aa
12.4 kDa
No 0
SUN1-024
ENSP00000392595
ENST00000450881
H7C019 [Direct mapping]
SUN domain-containing protein 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
171 aa
19 kDa
No 1
SUN1-027
ENSP00000414279
ENST00000419312
H7C3X3 [Direct mapping]
SUN domain-containing protein 1
Show all
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
158 aa
16.8 kDa
No 0
SUN1-201
ENSP00000392309
ENST00000425407
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0006998 [nuclear envelope organization]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
702 aa
77.9 kDa
No 2
SUN1-202
ENSP00000413439
ENST00000452783
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0006998 [nuclear envelope organization]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
682 aa
76.4 kDa
No 2
SUN1-203
ENSP00000395952
ENST00000457378
O94901 [Direct mapping]
SUN domain-containing protein 1
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0006998 [nuclear envelope organization]
GO:0031965 [nuclear membrane]
GO:0034993 [LINC complex]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043495 [protein anchor]
GO:0090286 [cytoskeletal anchoring at nuclear membrane]
GO:0090292 [nuclear matrix anchoring at nuclear membrane]
Show all
278 aa
30.4 kDa
No 0

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The Human Protein Atlas project is funded
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