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GKAP1

GENERAL INFORMATION

Gene name

 GKAP1

Gene description

 G kinase anchoring protein 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 2 antibodies.
HPA035117 , HPA035118
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GKAP1 (HGNC Symbol)

Synonyms

 FKSG21, GKAP42

Description

 G kinase anchoring protein 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

 9

Cytoband

 q21.32

Chromosome location (bp)

 83739421 - 83829516

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165113 (version 83.38)

Entrez gene

 80318

UniProt

 Q5VSY0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5VSY0

Antibodypedia

 GKAP1 antibodies

PROTEIN BROWSER
GKAP1-001
GKAP1-002
GKAP1-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GKAP1-001
ENSP00000365550
ENST00000376371
Q5VSY0 [Direct mapping]
G kinase-anchoring protein 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0007165 [signal transduction]
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 366 aa
42.1 kDa 		No 0
GKAP1-002
ENSP00000365544
ENST00000376365
Q5VSY0 [Direct mapping]
G kinase-anchoring protein 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0007165 [signal transduction]
Show all
 315 aa
36.1 kDa 		No 0
GKAP1-007
ENSP00000417621
ENST00000485742
C9J9D2 [Direct mapping]
G kinase-anchoring protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005794 [Golgi apparatus]
GO:0007165 [signal transduction]
Show all
 54 aa
5.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.