Cell atlas - ZNF598 - The Human Protein Atlas

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ZNF598

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	ZNF598
Gene description	Zinc finger protein 598
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA041760 , HPA041896
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane & cytosol.

Main location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA041760	A-431	Plasma membrane
HPA041760	A-431	Cytosol
HPA041760	U-2 OS	Plasma membrane
HPA041760	U-2 OS	Cytosol
HPA041760	U-251 MG	Plasma membrane
HPA041760	U-251 MG	Cytosol
HPA041896	A-431	Cytosol
HPA041896	U-2 OS	Cytosol
HPA041896	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ZNF598 (HGNC Symbol)
Synonyms	FLJ00086
Description	Zinc finger protein 598 (HGNC Symbol)
Entrez gene summary	Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. [provided by RefSeq, Oct 2012]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	1997654 - 2009823
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167962 (version 83.38)
Entrez gene	90850
UniProt	Q86UK7 (UniProt - Evidence at protein level)
neXtProt	NX_Q86UK7
Antibodypedia	ZNF598 antibodies

PROTEIN BROWSER

ZNF598-001	ZNF598-004	ZNF598-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF598-001 ENSP00000455882 ENST00000563630	H3BQQ2 [Direct mapping] Zinc finger protein 598 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	849 aa 93.3 kDa	No	0
ZNF598-004 ENSP00000455308 ENST00000562103	H3BQQ2 [Direct mapping] Zinc finger protein 598 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	849 aa 93.3 kDa	No	0
ZNF598-201 ENSP00000411409 ENST00000431526	Q86UK7 [Direct mapping] Zinc finger protein 598 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	904 aa 98.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.