Expression of PLA2G4F in cancer - Summary

CANCER ATLAS

Gene description

Phospholipase A2, group IVF

Protein class

Enzymes, Predicted intracellular proteins, RAS pathway related proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Urothelial cancer

STAINING SUMMARY

HPA056752

GENE INFORMATION
Gene name	PLA2G4F (HGNC Symbol)
Synonyms	PLA2G4F/Z
Description	Phospholipase A2, group IVF (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	42139034 - 42156636
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168907 (version 83.38)
Entrez gene	255189
UniProt	Q68DD2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q68DD2
Antibodypedia	PLA2G4F antibodies

PROTEIN BROWSER

PLA2G4F-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLA2G4F-001 ENSP00000380442 ENST00000397272	Q68DD2 [Direct mapping] Cytosolic phospholipase A2 zeta Show all	Enzymes ENZYME proteins Hydrolases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001516 [prostaglandin biosynthetic process] GO:0004620 [phospholipase activity] GO:0004622 [lysophospholipase activity] GO:0004623 [phospholipase A2 activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0008152 [metabolic process] GO:0009395 [phospholipid catabolic process] GO:0015908 [fatty acid transport] GO:0031982 [vesicle] GO:0032587 [ruffle membrane] GO:0036148 [phosphatidylglycerol acyl-chain remodeling] GO:0036149 [phosphatidylinositol acyl-chain remodeling] GO:0036150 [phosphatidylserine acyl-chain remodeling] GO:0036151 [phosphatidylcholine acyl-chain remodeling] GO:0036152 [phosphatidylethanolamine acyl-chain remodeling] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0046872 [metal ion binding] GO:0047498 [calcium-dependent phospholipase A2 activity] GO:0050482 [arachidonic acid secretion] GO:0071236 [cellular response to antibiotic] GO:0071407 [cellular response to organic cyclic compound] Show all	849 aa 95.1 kDa	No	0