Tissue expression of ELSPBP1 - Summary - The Human Protein Atlas

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ELSPBP1

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ELSPBP1
Gene description	Epididymal sperm binding protein 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (epididymis)
GTEx:	Tissue enhanced (testis)
FANTOM5:	Tissue enriched (epididymis)

Protein evidence

Evidence at protein level

Protein expression

Luminal membranous expression in epididymis with positivity in epididymal lumen.

DATA RELIABILITY
Data reliability description	External characterization data supports antibody staining but no internal RNA data available for correlation. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA044256 , HPA050341
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (epididymis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (epididymis)

GENE INFORMATION
Gene name	ELSPBP1 (HGNC Symbol)
Synonyms	E12, EDDM12, HE12
Description	Epididymal sperm binding protein 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the sperm-coating protein family of epididymal origin. This protein and its canine homolog are the first known examples of proteins with four tandemly arranged fibronectin type 2 (Fn2) domains in the Fn2-module protein family. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	47994651 - 48025153
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169393 (version 83.38)
Entrez gene	64100
UniProt	Q96BH3 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BH3
Antibodypedia	ELSPBP1 antibodies

PROTEIN BROWSER

ELSPBP1-001	ELSPBP1-002	ELSPBP1-003	ELSPBP1-004	ELSPBP1-005	ELSPBP1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ELSPBP1-001 ENSP00000340660 ENST00000339841	Q96BH3 [Direct mapping] Epididymal sperm-binding protein 1 Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0007338 [single fertilization] Show all	223 aa 26.1 kDa	No	0
ELSPBP1-002 ENSP00000471690 ENST00000597519	M0R179 [Direct mapping] Epididymal sperm-binding protein 1 Show all	TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		75 aa 8.8 kDa	Yes	0
ELSPBP1-003 ENSP00000470903 ENST00000596043	M0R006 [Direct mapping] Epididymal sperm-binding protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		150 aa 17.5 kDa	Yes	0
ELSPBP1-004 ENSP00000472960 ENST00000593782	M0R331 [Direct mapping] Epididymal sperm-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 17.9 kDa	No	0
ELSPBP1-005 ENSP00000470551 ENST00000593413	M0QZH6 [Direct mapping] Epididymal sperm-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		76 aa 8.9 kDa	No	0
ELSPBP1-201 ENSP00000481506 ENST00000619003	A0A087WY45 [Direct mapping] Epididymal sperm-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		220 aa 25.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.