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RBKS

GENERAL INFORMATION

Gene name

 RBKS

Gene description

 Ribokinase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (adrenal gland)
GTEx:Tissue enhanced (adrenal gland)
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression, highly abundant in adrenal gland.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 2 antibodies.
HPA019725 , HPA028285
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adrenal gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adrenal gland)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RBKS (HGNC Symbol)

Synonyms

 DKFZp686G13268, RBSK

Description

 Ribokinase (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Chromosome

 2

Cytoband

 p23.2

Chromosome location (bp)

 27781364 - 27891098

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000171174 (version 83.38)

Entrez gene

 64080

UniProt

 Q9H477 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H477

Antibodypedia

 RBKS antibodies

PROTEIN BROWSER
RBKS-001
RBKS-004
RBKS-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBKS-001
ENSP00000306817
ENST00000302188
Q9H477 [Direct mapping]
Ribokinase
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Enzymes
   ENZYME proteins
   Transferases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004747 [ribokinase activity]
GO:0005524 [ATP binding]
GO:0006014 [D-ribose metabolic process]
GO:0016773 [phosphotransferase activity, alcohol group as acceptor]
GO:0019303 [D-ribose catabolic process]
GO:0046835 [carbohydrate phosphorylation]
GO:0070062 [extracellular exosome]
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 322 aa
34.1 kDa 		No 0
RBKS-004
ENSP00000393558
ENST00000458185
H7C091 [Direct mapping]
Ribokinase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 147 aa
15.5 kDa 		No 0
RBKS-201
ENSP00000483033
ENST00000612015
A0A087X015 [Direct mapping]
Ribokinase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 18 aa
2.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.