Expression of OTP in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Orthopedia homeobox

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039365

GENE INFORMATION
Gene name	OTP
Synonyms
Description	Orthopedia homeobox (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q14.1
Chromosome location (bp)	77628712 - 77639688
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171540 (version 83.38)
Entrez gene	23440
UniProt	Q5XKR4 (UniProt - Evidence at protein level)
neXtProt	NX_Q5XKR4
Antibodypedia	OTP antibodies

PROTEIN BROWSER

OTP-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OTP-001 ENSP00000302814 ENST00000306422	Q5XKR4 [Direct mapping] Homeobox protein orthopedia Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0002052 [positive regulation of neuroblast proliferation] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0021879 [forebrain neuron differentiation] GO:0021979 [hypothalamus cell differentiation] GO:0021985 [neurohypophysis development] GO:0043565 [sequence-specific DNA binding] Show all	325 aa 34.2 kDa	No	0