Expression of ZNF449 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger protein 449

Protein class

Predicted intracellular proteins, Predicted secreted proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018079

GENE INFORMATION
Gene name	ZNF449 (HGNC Symbol)
Synonyms	FLJ23614, ZSCAN19
Description	Zinc finger protein 449 (HGNC Symbol)
Entrez gene summary	This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010]
Chromosome	X
Cytoband	q26.3
Chromosome location (bp)	135344796 - 135363152
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173275 (version 83.38)
Entrez gene	203523
UniProt	Q6P9G9 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P9G9
Antibodypedia	ZNF449 antibodies

PROTEIN BROWSER

ZNF449-001	ZNF449-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF449-001 ENSP00000359797 ENST00000370761	Q6P9G9 [Direct mapping] Zinc finger protein 449 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	164 aa 19.2 kDa	No	0
ZNF449-002 ENSP00000339585 ENST00000339249	Q6P9G9 [Direct mapping] Zinc finger protein 449 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	518 aa 59.9 kDa	Yes	0