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– GENE INFO –
Gene name
Protein class
Chromosome
External id
– DATA AVAILABILITY –
Has protein data
– DATA RELIABILITY –
Reliability score tissue (IHC)
Reliability score mouse brain
Reliability score cells (ICC/IF)
– ANTIBODY VALIDATION –
Protein array
Western blot
Immunohistochemistry
Immunocytochemistry
– PRIMARY DATA –
Subcellular localization
Tissue expression (IHC)
RNA tissue category
RNA cell category
Tissue detectable (RNA)
Cell line detectable (RNA)
– PROTEIN EVIDENCE –
Evidence summary
UniProt evidence
HPA evidence
MS evidence
– ANTIBODIES –
With antibodies
– EXTRA –
Sort by
Term
Gene name
Class
Blood group antigen proteins
Cancer-related genes
Candidate cardiovascular disease genes
CD markers
Citric acid cycle related proteins
Disease related genes
Enzymes
FDA approved drug targets
G-protein coupled receptors
Mapped to UniProt SWISS-PROT
Nuclear receptors
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RAS pathway related proteins
Ribosomal proteins
RNA polymerase related proteins
Transcription factors
Transporters
Voltage-gated ion channels
Subclass
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
MT
Unmapped
X
Y
External id
In atlas
Tissue
Cancer
Cell
Reliability
Supported
Approved
Uncertain
Reliability
Supported
Approved
Reliability
Validated
Supported
Approved
Uncertain
Validation
Supported
Approved
Method
Formal
Standard
Validation
Method
Formal
Standard
Validation
Method
Formal
Standard
Validation
Location
Actin filaments
Aggresome
Cell Junctions
Centrosome
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
Endoplasmic reticulum
Endosomes
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Lipid droplets
Lysosomes
Microtubule ends
Microtubule organizing center
Microtubules
Midbody
Midbody ring
Mitochondria
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoplasm
Nucleus
Peroxisomes
Plasma membrane
Rods & Rings
Vesicles
Searches
– RELIABILITY –
Validated
Supported
Approved
Uncertain
– SUBCELLULAR VARIATION –
Intensity variation
Spatial variation
Cell cycle intensity correlation
Cell cycle spatial correlation
Cell cycle biologically
Custom data cell cycle dependant
– MULTILOCALIZATION –
Multilocalizing
Localizing 1
Localizing 2
Localizing 3
Localizing 4
Localizing 5
Tissue
Any
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Caudate
Cerebellum
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium 1
Endometrium 2
Epididymis
Esophagus
Eye
Fallopian tube
Gallbladder
Hair
Heart muscle
Hippocampus
Hypothalamus
Kidney
Lactating breast
Liver
Lung
Lymph node
Nasopharynx
Oral mucosa
Ovary
Pancreas
Parathyroid gland
Pituitary gland
Placenta
Prostate
Rectum
Retina
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Skin 1
Skin 2
Small intestine
Smooth muscle
Soft tissue 1
Soft tissue 2
Spleen
Stomach 1
Stomach 2
Testis
Thyroid gland
Tonsil
Urinary bladder
Vagina
Cell type
Expression
Not detected
Low
Medium
High
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Parathyroid gland
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Specificity
Tissue enriched
Group enriched
Tissue enhanced
Elevated
Expressed in all
Mixed
Not detected
Cell line
Any
HEL
HL-60
HMC-1
K-562
NB-4
THP-1
U-937
Daudi
HDLM-2
Karpas-707
MOLT-4
REH
RPMI-8226
U-266/70
U-266/84
U-698
AF22
SH-SY5Y
U-138 MG
U-251 MG
U-87 MG
A549
SCLC-21H
CACO-2
CAPAN-2
Hep G2
AN3-CA
EFO-21
HeLa
MCF7
SiHa
SK-BR-3
T-47d
HEK 293
NTERA-2
PC-3
RPTEC TERT1
RT4
A-431
HaCaT
SK-MEL-30
WM-115
ASC TERT1
LHCN-M2
RH-30
U-2 OS
U-2197
BEWO
hTCEpi
BJ
BJ hTERT+
BJ hTERT+ SV40 Large T+
BJ hTERT+ SV40 Large T+ RasG12V
HBF TERT88
HUVEC TERT2
TIME
Specificity
Cell line enriched
Group enriched
Cell line enhanced
Elevated
Expressed in all
Mixed
Not detected
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Parathyroid gland
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Detectable
Yes
No
Cell line
Any
A-431
A549
AF22
AN3-CA
ASC TERT1
BEWO
BJ
BJ hTERT+
BJ hTERT+ SV40 Large T+
BJ hTERT+ SV40 Large T+ RasG12V
CACO-2
CAPAN-2
Daudi
EFO-21
HaCaT
HBF TERT88
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HL-60
HMC-1
hTCEpi
HUVEC TERT2
K-562
Karpas-707
LHCN-M2
MCF7
MOLT-4
NB-4
NTERA-2
PC-3
REH
RH-30
RPMI-8226
RPTEC TERT1
RT4
SCLC-21H
SH-SY5Y
SiHa
SK-BR-3
SK-MEL-30
T-47d
THP-1
TIME
U-138 MG
U-2 OS
U-2197
U-251 MG
U-266/70
U-266/84
U-698
U-87 MG
U-937
WM-115
Detectable
Yes
No
Category
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Antibodies
Yes
No
Column
gene
position
tissue specific score
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ZNF449
TISSUE
CELL
CANCER
CANCER ATLAS
GLIOMA
GENE/PROTEIN
Antibody validation
Dictionary
Glioma
GLIOMA
Antibody HPA018079
Antibody staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
Rare
Negative
Location
Cytoplasmic/membranous,nuclear
Cytoplasmic/membranous
Nuclear
None
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