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Few urothelial, cervical, pancreatic, lung, prostate and colorectal cancers showed weak to moderate cytoplasmic staining in cases combined with membranous immunoreactivity. Cancer cells in general were negative.
GENE INFORMATION
Gene name
MARCH3 (HGNC Symbol)
Synonyms
MARCH-III, MGC48332, RNF173
Description
Membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein ligase that may be involved in regulation of the endosomal transport pathway. [provided by RefSeq, Mar 2013]