Cell atlas - MARCH3 - The Human Protein Atlas

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MARCH3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MARCH3
Gene description	Membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (TIME, HUVEC TERT2)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (TIME, HUVEC TERT2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MARCH3 (HGNC Symbol)
Synonyms	MARCH-III, MGC48332, RNF173
Description	Membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein ligase that may be involved in regulation of the endosomal transport pathway. [provided by RefSeq, Mar 2013]
Chromosome	5
Cytoband	q23.2
Chromosome location (bp)	126867714 - 127030808
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000173926 (version 83.38)
Entrez gene	115123
UniProt	Q86UD3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86UD3
Antibodypedia	MARCH3 antibodies

PROTEIN BROWSER

MARCH3-001	MARCH3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MARCH3-001 ENSP00000309141 ENST00000308660	Q86UD3 [Direct mapping] E3 ubiquitin-protein ligase MARCH3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005764 [lysosome] GO:0005768 [endosome] GO:0006897 [endocytosis] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0030659 [cytoplasmic vesicle membrane] GO:0031901 [early endosome membrane] Show all	253 aa 28.5 kDa	No	2
MARCH3-002 ENSP00000421979 ENST00000515241	Q86UD3 [Direct mapping] E3 ubiquitin-protein ligase MARCH3 Show all	Predicted intracellular proteins Show all	GO:0005764 [lysosome] GO:0005768 [endosome] GO:0006897 [endocytosis] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0030659 [cytoplasmic vesicle membrane] GO:0031901 [early endosome membrane] Show all	138 aa 15.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.