Cell atlas - ZNF266 - The Human Protein Atlas

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ZNF266

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus
	Rods & Rings
	Vesicles

Human cell
	Cytosol
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	ZNF266
Gene description	Zinc finger protein 266
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles. In addition localized to the nucleus & rods & rings.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (validated)
Additional location	In addition localized to the Nucleus (approved), Rods & Rings (approved)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA026836 , HPA054110
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ASSAYS

RNA expression

Human cells

Custom data

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles. In addition localized to the nucleus & rods & rings.

Main location

Vesicles (validated)

Additional location

Nucleus (approved), Rods & Rings (approved)


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Antibody	Cell line	Location
HPA026836	HEK 293	Nucleus
HPA026836	HEK 293	Vesicles
HPA026836	HeLa	Nucleus
HPA026836	HeLa	Vesicles
HPA026836	U-2 OS	Nucleus
		Vesicles
		Cytosol
HPA054110	A-431	Vesicles
HPA054110	HeLa	Vesicles
HPA054110	HeLa	Rods & Rings
HPA054110	U-2 OS	Vesicles

CUSTOM DATA


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Thumbnail	Antibody	Cell line	Assay	Description
	HPA054110	U-2 OS	Image	U-2 OS cells were treated with Ribavirin to induce the formation of Rods & Rings. Co-localization shows that ZNF266 localizes to Rods & Rings as the staining overlaps with a marker for Rods & Rings.

GENE INFORMATION
Gene name	ZNF266 (HGNC Symbol)
Synonyms	HZF1
Description	Zinc finger protein 266 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein containing many tandem zinc-finger motifs. Zinc fingers are protein or nucleic acid-binding domains, and may be involved in a variety of functions, including regulation of transcription. This gene is located in a cluster of similar genes encoding zinc finger proteins on chromosome 19. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Sep 2012]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	9412598 - 9435578
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174652 (version 83.38)
Entrez gene	10781
UniProt	Q14584 (UniProt - Evidence at protein level)
neXtProt	NX_Q14584
Antibodypedia	ZNF266 antibodies

PROTEIN BROWSER

ZNF266-001	ZNF266-002	ZNF266-003	ZNF266-004	ZNF266-005	ZNF266-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF266-001 ENSP00000468491 ENST00000588221	Q14584 [Direct mapping] Zinc finger protein 266 A0A024R7B6 [Target identity:100%; Query identity:100%] Zinc finger protein 266, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	549 aa 62.1 kDa	No	0
ZNF266-002 ENSP00000466714 ENST00000592904	Q14584 [Direct mapping] Zinc finger protein 266 A0A024R7B6 [Target identity:100%; Query identity:100%] Zinc finger protein 266, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	549 aa 62.1 kDa	No	0
ZNF266-003 ENSP00000467151 ENST00000588933	Q14584 [Direct mapping] Zinc finger protein 266 A0A024R7B6 [Target identity:100%; Query identity:100%] Zinc finger protein 266, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	549 aa 62.1 kDa	No	0
ZNF266-004 ENSP00000467403 ENST00000592292	Q14584 [Direct mapping] Zinc finger protein 266 A0A024R7B6 [Target identity:100%; Query identity:100%] Zinc finger protein 266, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	549 aa 62.1 kDa	No	0
ZNF266-005 ENSP00000467315 ENST00000590306	Q14584 [Direct mapping] Zinc finger protein 266 A0A024R7B6 [Target identity:100%; Query identity:100%] Zinc finger protein 266, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	549 aa 62.1 kDa	No	0
ZNF266-007 ENSP00000467923 ENST00000591213	K7EQP7 [Direct mapping] Zinc finger protein 266 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	72 aa 8.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.