Expression of STAP2 in cancer - Summary

CANCER ATLAS

Gene description

Signal transducing adaptor family member 2

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA002375	HPA027761

GENE INFORMATION
Gene name	STAP2 (HGNC Symbol)
Synonyms	BKS, STAP-2
Description	Signal transducing adaptor family member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4324043 - 4342786
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178078 (version 83.38)
Entrez gene	55620
UniProt	Q9UGK3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UGK3
Antibodypedia	STAP2 antibodies

PROTEIN BROWSER

STAP2-002	STAP2-003	STAP2-006	STAP2-009	STAP2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STAP2-002 ENSP00000468927 ENST00000600324	Q9UGK3 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] Show all	449 aa 49.6 kDa	No	0
STAP2-003 ENSP00000471052 ENST00000594605	Q9UGK3 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	403 aa 44.9 kDa	No	0
STAP2-006 ENSP00000472851 ENST00000601482	M0R2W4 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		260 aa 29.4 kDa	No	0
STAP2-009 ENSP00000471281 ENST00000598443	M0R0J5 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		159 aa 17.5 kDa	No	0
STAP2-010 ENSP00000469657 ENST00000601956	M0QY82 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		106 aa 11.1 kDa	No	0