Tissue expression of STAP2 - Summary - The Human Protein Atlas

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STAP2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	STAP2
Gene description	Signal transducing adaptor family member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Tissue enhanced (small intestine)

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, highest levels in cns and gastrointestinal tract.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA002375 , HPA027761
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

N/A

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine)

GENE INFORMATION
Gene name	STAP2 (HGNC Symbol)
Synonyms	BKS, STAP-2
Description	Signal transducing adaptor family member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4324043 - 4342786
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178078 (version 83.38)
Entrez gene	55620
UniProt	Q9UGK3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UGK3
Antibodypedia	STAP2 antibodies

PROTEIN BROWSER

STAP2-002	STAP2-003	STAP2-006	STAP2-009	STAP2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STAP2-002 ENSP00000468927 ENST00000600324	Q9UGK3 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] Show all	449 aa 49.6 kDa	No	0
STAP2-003 ENSP00000471052 ENST00000594605	Q9UGK3 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	403 aa 44.9 kDa	No	0
STAP2-006 ENSP00000472851 ENST00000601482	M0R2W4 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		260 aa 29.4 kDa	No	0
STAP2-009 ENSP00000471281 ENST00000598443	M0R0J5 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		159 aa 17.5 kDa	No	0
STAP2-010 ENSP00000469657 ENST00000601956	M0QY82 [Direct mapping] Signal-transducing adaptor protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		106 aa 11.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.