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MRFAP1

GENERAL INFORMATION

Gene name

 MRFAP1

Gene description

 Morf4 family associated protein 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Expression in the brain.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Approved based on 1 antibody.
CAB042447
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MRFAP1 (HGNC Symbol)

Synonyms

 PAM14, PGR1

Description

 Morf4 family associated protein 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

 4

Cytoband

 p16.1

Chromosome location (bp)

 6640091 - 6642745

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179010 (version 83.38)

Entrez gene

 93621

UniProt

 Q9Y605 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y605

Antibodypedia

 MRFAP1 antibodies

PROTEIN BROWSER
MRFAP1-001
MRFAP1-003
MRFAP1-007
MRFAP1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRFAP1-001
ENSP00000318352
ENST00000320912
Q9Y605 [Direct mapping]
MORF4 family-associated protein 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 127 aa
14.6 kDa 		No 0
MRFAP1-003
ENSP00000372024
ENST00000382581
Q9Y605 [Direct mapping]
MORF4 family-associated protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 127 aa
14.6 kDa 		No 0
MRFAP1-007
ENSP00000422065
ENST00000507420
Q9Y605 [Direct mapping]
MORF4 family-associated protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 127 aa
14.6 kDa 		No 0
MRFAP1-201
ENSP00000478229
ENST00000617365
A0A087WTY9 [Direct mapping]
MORF4 family-associated protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 103 aa
11.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.