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Most malignancies displayed strong nuclear staining, often combined with cytoplasmic positivity.
GENE INFORMATION
Gene name
ALYREF (HGNC Symbol)
Synonyms
ALY, ALY/REF, BEF, REF, THOC4
Description
Aly/REF export factor (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]
