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TBL3

CANCER ATLAS

Gene description

 Transducin (beta)-like 3

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042562

GENE INFORMATION

Gene name

 TBL3 (HGNC Symbol)

Synonyms

 SAZD, UTP13

Description

 Transducin (beta)-like 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 1972037 - 1982933

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000183751 (version 83.38)

Entrez gene

 10607

UniProt

 Q12788 (UniProt - Evidence at protein level)

neXtProt

 NX_Q12788

Antibodypedia

 TBL3 antibodies

PROTEIN BROWSER
TBL3-001
TBL3-004
TBL3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TBL3-001
ENSP00000454836
ENST00000568546
Q12788 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006364 [rRNA processing]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
GO:0044822 [poly(A) RNA binding]
Show all
 808 aa
89 kDa 		No 0
TBL3-004
ENSP00000331815
ENST00000332704
J3KNP2 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0006364 [rRNA processing]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
Show all
 697 aa
77 kDa 		No 0
TBL3-201
ENSP00000481995
ENST00000615855
A0A087WYP7 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
Show all
 518 aa
55.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.