Fields »
ABOUT
HELP
BLOG
TBL3

GENERAL INFORMATION

Gene name

 TBL3

Gene description

 Transducin (beta)-like 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear or nucleolar expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA042562
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TBL3 (HGNC Symbol)

Synonyms

 SAZD, UTP13

Description

 Transducin (beta)-like 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 1972037 - 1982933

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000183751 (version 83.38)

Entrez gene

 10607

UniProt

 Q12788 (UniProt - Evidence at protein level)

neXtProt

 NX_Q12788

Antibodypedia

 TBL3 antibodies

PROTEIN BROWSER
TBL3-001
TBL3-004
TBL3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TBL3-001
ENSP00000454836
ENST00000568546
Q12788 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006364 [rRNA processing]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
GO:0044822 [poly(A) RNA binding]
Show all
 808 aa
89 kDa 		No 0
TBL3-004
ENSP00000331815
ENST00000332704
J3KNP2 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0006364 [rRNA processing]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
Show all
 697 aa
77 kDa 		No 0
TBL3-201
ENSP00000481995
ENST00000615855
A0A087WYP7 [Direct mapping]
Transducin beta-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005515 [protein binding]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
Show all
 518 aa
55.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.