Tissue expression of B3GALT5 - Summary - The Human Protein Atlas

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B3GALT5

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	B3GALT5
Gene description	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (rectum, small intestine, duodenum, colon, gallbladder)
GTEx:	Tissue enhanced (small intestine)
FANTOM5:	Tissue enhanced (caudate, tonsil)

Protein evidence

Evidence at protein level

Protein expression

Membranous expression mainly in the gastrointestinal tract.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA054092 , HPA054684
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Small intestine

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (rectum, small intestine, duodenum, colon, gallbladder)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (caudate, tonsil)

GENE INFORMATION
Gene name	B3GALT5 (HGNC Symbol)
Synonyms	B3GalT-V, B3T5, beta3Gal-T5, GLCT5
Description	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants have been observed for this gene, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2013]
Chromosome	21
Cytoband	q22.2
Chromosome location (bp)	39556442 - 39673137
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183778 (version 83.38)
Entrez gene	10317
UniProt	Q9Y2C3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y2C3
Antibodypedia	B3GALT5 antibodies

PROTEIN BROWSER

B3GALT5-001	B3GALT5-002	B3GALT5-201	B3GALT5-202	B3GALT5-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B3GALT5-001 ENSP00000369994 ENST00000380620	Q9Y2C3 [Direct mapping] Beta-1,3-galactosyltransferase 5 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008378 [galactosyltransferase activity] GO:0008499 [UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	310 aa 36.2 kDa	Yes	0
B3GALT5-002 ENSP00000369992 ENST00000380618	Q9Y2C3 [Direct mapping] Beta-1,3-galactosyltransferase 5 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008378 [galactosyltransferase activity] GO:0008499 [UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	310 aa 36.2 kDa	Yes	0
B3GALT5-201 ENSP00000343318 ENST00000343118	Q9Y2C3 [Direct mapping] Beta-1,3-galactosyltransferase 5 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008378 [galactosyltransferase activity] GO:0008499 [UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	310 aa 36.2 kDa	Yes	0
B3GALT5-202 ENSP00000381699 ENST00000398714	A0A0A0MS93 [Direct mapping] Beta-1,3-galactosyltransferase 5 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008378 [galactosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	314 aa 36.7 kDa	No	0
B3GALT5-203 ENSP00000480285 ENST00000615480	Q9Y2C3 [Direct mapping] Beta-1,3-galactosyltransferase 5 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008378 [galactosyltransferase activity] GO:0008499 [UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	310 aa 36.2 kDa	Yes	0

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The Project

The Human Protein Atlas

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