Expression of RALGAPA2 in cancer - Summary

CANCER ATLAS

Gene description

Ral GTPase activating protein, alpha subunit 2 (catalytic)

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042707	HPA043622

GENE INFORMATION
Gene name	RALGAPA2 (HGNC Symbol)
Synonyms	AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2
Description	Ral GTPase activating protein, alpha subunit 2 (catalytic) (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	p11.23
Chromosome location (bp)	20389552 - 20712488
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188559 (version 83.38)
Entrez gene	57186
UniProt	Q2PPJ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q2PPJ7
Antibodypedia	RALGAPA2 antibodies

PROTEIN BROWSER

RALGAPA2-002	RALGAPA2-007	RALGAPA2-008	RALGAPA2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RALGAPA2-002 ENSP00000400085 ENST00000430436	H7C1F9 [Direct mapping] Ral GTPase-activating protein subunit alpha-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	1740 aa 194.9 kDa	No	2
RALGAPA2-007 ENSP00000388695 ENST00000427175	H7BZA8 [Direct mapping] Ral GTPase-activating protein subunit alpha-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	250 aa 28.1 kDa	No	0
RALGAPA2-008 ENSP00000202677 ENST00000202677	Q2PPJ7 [Direct mapping] Ral GTPase-activating protein subunit alpha-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0032484 [Ral protein signal transduction] GO:0032880 [regulation of protein localization] GO:0046982 [protein heterodimerization activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0060178 [regulation of exocyst localization] GO:0061024 [membrane organization] GO:0090630 [activation of GTPase activity] Show all	1873 aa 210.8 kDa	No	2
RALGAPA2-201 ENSP00000481660 ENST00000620717	A0A087WYA8 [Direct mapping] Ral GTPase-activating protein subunit alpha-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	237 aa 26.9 kDa	No	0