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Distinct positivity in plasma and expression in extracellular matrix in a majority of tissues.
DATA RELIABILITY
Data reliability description
Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
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SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)
P01009 [Direct mapping] Alpha-1-antitrypsin Short peptide from AAT E9KL23 [Target identity:100%; Query identity:100%] Epididymis secretory sperm binding protein Li 44a
Show all
SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Candidate cardiovascular disease genes Disease related genes Protein evidence (Ezkurdia et al 2014)