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Cancer tissues generally showed moderate to strong membranous and cytoplasmic staining. A majority of renal cancers, gliomas, lymphomas and melanomas were weakly stained or negative.
A single case of papillary adenocarcinoma of thyroid exhibited strong cytoplasmic staining. Several cases of melanoma, colorectal, breast, ovarian and pancreatic cancer displayed moderate cytoplasmic positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
RBM20
Synonyms
Description
RNA binding motif protein 20 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that binds RNA and regulates splicing. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Apr 2014]
