Tissue expression of RBM20 - Summary - The Human Protein Atlas

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RBM20

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RBM20
Gene description	RNA binding motif protein 20
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (heart muscle)
GTEx:	Tissue enhanced (heart muscle)
FANTOM5:	Tissue enhanced (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in cardiac myocytes.

DATA RELIABILITY
Data reliability description	External characterization data supports antibody staining. Pending external verification. Cytoplasmic positivity observed and disregarded.
Reliability score	Uncertain based on 2 antibodies. HPA035806 , HPA037703
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle, skeletal muscle)

GENE INFORMATION
Gene name	RBM20
Synonyms
Description	RNA binding motif protein 20 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that binds RNA and regulates splicing. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Apr 2014]
Chromosome	10
Cytoband	q25.2
Chromosome location (bp)	110644397 - 110839469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203867 (version 83.38)
Entrez gene	282996
UniProt	Q5T481 (UniProt - Evidence at protein level)
neXtProt	NX_Q5T481
Antibodypedia	RBM20 antibodies

PROTEIN BROWSER

RBM20-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM20-001 ENSP00000358532 ENST00000369519	Q5T481 [Direct mapping] RNA-binding protein 20 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0007507 [heart development] GO:0008270 [zinc ion binding] GO:0008380 [RNA splicing] GO:0033120 [positive regulation of RNA splicing] Show all	1227 aa 134.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.