Cell atlas - TRIM15 - The Human Protein Atlas

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TRIM15

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	TRIM15
Gene description	Tripartite motif containing 15
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (HEL)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (HEL) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TRIM15 (HGNC Symbol)
Synonyms	RNF93, ZNF178, ZNFB7
Description	Tripartite motif containing 15 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30163206 - 30172696
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204610 (version 83.38)
Entrez gene	89870
UniProt	Q9C019 (UniProt - Evidence at protein level)
neXtProt	NX_Q9C019
Antibodypedia	TRIM15 antibodies

PROTEIN BROWSER

TRIM15-001	TRIM15-002	TRIM15-202	TRIM15-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM15-001 ENSP00000365884 ENST00000376694	Q9C019 [Direct mapping] Tripartite motif-containing protein 15 Q5SRL0 [Target identity:100%; Query identity:100%] Tripartite motif-containing 15; cDNA FLJ75016, highly similar to Homo sapiens tripartite motif-containing 15 (TRIM15), transcript variant 1, mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0007500 [mesodermal cell fate determination] GO:0008270 [zinc ion binding] GO:0032481 [positive regulation of type I interferon production] GO:0045087 [innate immune response] GO:0046872 [metal ion binding] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0051092 [positive regulation of NF-kappaB transcription factor activity] GO:1900246 [positive regulation of RIG-I signaling pathway] GO:1901253 [negative regulation of intracellular transport of viral material] GO:1902187 [negative regulation of viral release from host cell] Show all	465 aa 52.1 kDa	No	0
TRIM15-002 ENSP00000398285 ENST00000433744	H0Y5R0 [Direct mapping] Tripartite motif-containing protein 15 Show all	Predicted intracellular proteins Show all		164 aa 19.2 kDa	No	0
TRIM15-202 ENSP00000365878 ENST00000376688	Q9C019 [Direct mapping] Tripartite motif-containing protein 15 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0007500 [mesodermal cell fate determination] GO:0008270 [zinc ion binding] GO:0032481 [positive regulation of type I interferon production] GO:0045087 [innate immune response] GO:0046872 [metal ion binding] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0051092 [positive regulation of NF-kappaB transcription factor activity] GO:1900246 [positive regulation of RIG-I signaling pathway] GO:1901253 [negative regulation of intracellular transport of viral material] GO:1902187 [negative regulation of viral release from host cell] Show all	115 aa 12.3 kDa	No	0
TRIM15-203 ENSP00000484001 ENST00000619857	A0A087X199 [Direct mapping] Tripartite motif-containing protein 15 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	396 aa 44.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.