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Several cases of lymphomas, colorectal, breast, endometrial, testicular and liver cancers exhibited weak to moderate membranous and/or cytoplasmic positivity. Strong staining was observed in a single case of colorectal, renal and liver cancer. Other cancers were generally negative.
GENE INFORMATION
Gene name
IGFL2 (HGNC Symbol)
Synonyms
UNQ645
Description
IGF-like family member 2 (HGNC Symbol)
Entrez gene summary
IGFL2 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]