Tissue expression of IGFL2 - Summary - The Human Protein Atlas

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IGFL2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	IGFL2
Gene description	IGF-like family member 2
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (skin)
GTEx:	Group enriched (skin, testis)
FANTOM5:	Not detected

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA059137
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skin, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	IGFL2 (HGNC Symbol)
Synonyms	UNQ645
Description	IGF-like family member 2 (HGNC Symbol)
Entrez gene summary	IGFL2 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	46143106 - 46161299
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204866 (version 83.38)
Entrez gene	147920
UniProt	Q6UWQ7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UWQ7
Antibodypedia	IGFL2 antibodies

PROTEIN BROWSER

IGFL2-001	IGFL2-002	IGFL2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IGFL2-001 ENSP00000395219 ENST00000434646	Q6UWQ7 [Direct mapping] Insulin growth factor-like family member 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] Show all	130 aa 14.5 kDa	Yes	0
IGFL2-002 ENSP00000366922 ENST00000377693	Q6UWQ7 [Direct mapping] Insulin growth factor-like family member 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] Show all	119 aa 13.2 kDa	Yes	0
IGFL2-006 ENSP00000471085 ENST00000601052	M0R089 [Direct mapping] Insulin growth factor-like family member 2 Show all	Predicted intracellular proteins Show all		84 aa 9.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.