Cell atlas - GAGE1 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	GAGE1
Gene description	G antigen 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol. In addition localized to the Golgi apparatus. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Group enriched (AN3-CA, K-562)
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (uncertain), Cytosol (uncertain)
Additional location	In addition localized to the Golgi apparatus (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA043232
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (AN3-CA, K-562) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol. In addition localized to the Golgi apparatus. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Plasma membrane (uncertain), Cytosol (uncertain)

Additional location

Golgi apparatus (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA043232	A-431	Golgi apparatus
		Plasma membrane
		Cytosol
HPA043232	U-2 OS	Plasma membrane
HPA043232	U-2 OS	Cytosol

GENE INFORMATION
Gene name	GAGE1 (HGNC Symbol)
Synonyms	CT4.1
Description	G antigen 1 (HGNC Symbol)
Entrez gene summary	This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Chromosome	X
Cytoband	p11.23
Chromosome location (bp)	49589496 - 49608536
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205777 (version 83.38)
Entrez gene	2543
UniProt	Q13068 (UniProt - Evidence at protein level)
neXtProt	NX_Q13068
Antibodypedia	GAGE1 antibodies

PROTEIN BROWSER

GAGE1-002	GAGE1-201	GAGE1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GAGE1-002 ENSP00000371119 ENST00000381700	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0
GAGE1-201 ENSP00000482230 ENST00000610680	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0
GAGE1-202 ENSP00000484668 ENST00000619375	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0