Tissue expression of GAGE1 - Summary - The Human Protein Atlas

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GAGE1

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GAGE1
Gene description	G antigen 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Selective expression in spermatogonia.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA043232
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	GAGE1 (HGNC Symbol)
Synonyms	CT4.1
Description	G antigen 1 (HGNC Symbol)
Entrez gene summary	This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Chromosome	X
Cytoband	p11.23
Chromosome location (bp)	49589496 - 49608536
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205777 (version 83.38)
Entrez gene	2543
UniProt	Q13068 (UniProt - Evidence at protein level)
neXtProt	NX_Q13068
Antibodypedia	GAGE1 antibodies

PROTEIN BROWSER

GAGE1-002	GAGE1-201	GAGE1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GAGE1-002 ENSP00000371119 ENST00000381700	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0
GAGE1-201 ENSP00000482230 ENST00000610680	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0
GAGE1-202 ENSP00000484668 ENST00000619375	Q13068 [Target identity:100%; Query identity:100%] G antigen 4 Show all	Predicted intracellular proteins Show all		117 aa 12.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.