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Cancer tissues showed moderate cytoplasmic positivity with additional nuclear staining in several cases. A rare case of carcinoid, melanoma, seminoma, prostate and urothelial cancer were strongly stained. Several non-Hodgkins lymphomas and renal cancers were weakly stained.
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide]