Cell atlas - ZNF580 - The Human Protein Atlas

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ZNF580

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF580
Gene description	Zinc finger protein 580
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA054058
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA054058	HEK 293	Nucleus
	HPA054058	U-2 OS	Nucleus
	HPA054058	U-251 MG	Nucleoplasm

MOUSE CELLS

Main location

Not available

Mouse gene

ENSMUSG00000055633 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA054058	NIH 3T3	No staining

GENE INFORMATION
Gene name	ZNF580
Synonyms
Description	Zinc finger protein 580 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.42
Chromosome location (bp)	55635016 - 55643469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213015 (version 83.38)
Entrez gene	51157
UniProt	Q9UK33 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UK33
Antibodypedia	ZNF580 antibodies

PROTEIN BROWSER

ZNF580-001	ZNF580-002	ZNF580-003	ZNF580-004	ZNF580-005	ZNF580-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF580-001 ENSP00000320050 ENST00000325333	Q9UK33 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide] Show all	172 aa 18.8 kDa	No	0
ZNF580-002 ENSP00000443957 ENST00000543039	Q9UK33 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide] Show all	172 aa 18.8 kDa	No	0
ZNF580-003 ENSP00000467142 ENST00000592461	K7ENY2 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	104 aa 11.1 kDa	No	0
ZNF580-004 ENSP00000468407 ENST00000592881	K7ERU0 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	103 aa 11 kDa	No	0
ZNF580-005 ENSP00000465028 ENST00000590190	K7EJ53 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	22 aa 2.4 kDa	No	0
ZNF580-201 ENSP00000446126 ENST00000545125	Q9UK33 [Direct mapping] Zinc finger protein 580 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001938 [positive regulation of endothelial cell proliferation] GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0032757 [positive regulation of interleukin-8 production] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide] Show all	172 aa 18.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.