Cell atlas - IGSF23 - The Human Protein Atlas

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IGSF23

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Nucleus

Human cell
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	IGSF23
Gene description	Immunoglobulin superfamily, member 23
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus. In addition localized to the cell junctions.
RNA cell category	Cell line enhanced (CACO-2, SiHa, Hep G2)
Protein evidence	Evidence at transcript level
Main location	Localized to the Nucleus (approved)
Additional location	In addition localized to the Cell Junctions (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051811
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (CACO-2, SiHa, Hep G2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus. In addition localized to the cell junctions.

Main location

Nucleus (approved)

Additional location

Cell Junctions (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051811	CACO-2	Nucleus
	HPA051811	CACO-2	Cell Junctions
	HPA051811	Hep G2	Nucleus
	HPA051811	U-2 OS	Nucleus

GENE INFORMATION
Gene name	IGSF23
Synonyms
Description	Immunoglobulin superfamily, member 23 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Nov 2011]
Chromosome	19
Cytoband	q13.31
Chromosome location (bp)	44613630 - 44636781
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000216588 (version 83.38)
Entrez gene	147710
UniProt	A1L1A6 (UniProt - Evidence at transcript level)
neXtProt	NX_A1L1A6
Antibodypedia	IGSF23 antibodies

PROTEIN BROWSER

IGSF23-001	IGSF23-002	IGSF23-003	IGSF23-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IGSF23-001 ENSP00000407344 ENST00000441389	H0Y6S3 [Direct mapping] Immunoglobulin superfamily member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	138 aa 14.7 kDa	No	1
IGSF23-002 ENSP00000410629 ENST00000428245	H0Y773 [Direct mapping] Immunoglobulin superfamily member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	212 aa 22.6 kDa	Yes	1
IGSF23-003 ENSP00000385592 ENST00000402988	A1L1A6 [Direct mapping] Immunoglobulin superfamily member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	192 aa 20.6 kDa	No	1
IGSF23-004 ENSP00000465887 ENST00000592507	K7EL25 [Direct mapping] Immunoglobulin superfamily member 23 Show all	Predicted intracellular proteins Show all		66 aa 7.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.